Adaptation of the award-winning comic series created by Frank Miller. Interweaving multiple storylines from the series' history, the film paints a picture of the ultimate town through the eyes of its roughest characters. There's the street thug Marv (Mickey Rourke), whose desperate quest to find the killer of a prostitute named Goldie (Jaime King) will lead him to the foulest edges of town. Inhabiting many of those areas is Dwight (Clive Owen), a photographer in league with the sordid ladies of Sin City, headed by Gail (Rosario Dawson), who opens up a mess of trouble after tangling with a corrupt cop by the name of Jackie Boy (Benicio Del Toro). Finally, there's Hartigan (Bruce Willis), an ex-cop with a heart problem who's hell-bent on protecting a stripper named Nancy (Jessica Alba).

Josh Hartnett and Samuel L. Jackson star in this drama about a journalist whose life changes after he writes an article about a homeless man who was once a boxing legend. Reporter Erik Kernan Jr. (Hartnett) finds the opportunity to prove himself to his boss (Alan Alda) and his family by writing a heartfelt piece about a former professional boxer (Jackson) who has since fallen into homelessness and destitution and now spends his days raking through the rubbish bins of Denver. Writing the article leads to a soul-searching personal journey for Erik as he finds himself re-examining his own past and his relationship with his family.